Mercenary Mode
Successfully complete the game once on any either difficulty setting and wait for the credits to end, then save the "Next Game" file to unlock "The Mercenaries" mini-game. Start a new game, choose that saved game, then select "The Mercenaries" mode. This mode involves controlling Carlos, Mikhal, or Nikoli from the train to the starting room with a two minute timer. Killing the various opponents and rescuing civilians during the journey will add extra money and more time to the clock. A rank and money will be awarded after the game is completed. The money can be used to purchase better weapons and infinite ammunition.

Boutique Key
Successfully complete the game once and wait for the credits to end, then save the "Next Game" file to receive the key to the Boutique on the first street at the start of the game. Use the key to enter and change into an alternate costume.

Alternate Costumes
Successfully complete the game on the easy difficulty setting with any rank better than an F to unlock Jills costume from the original Resident Evil and Reginas costume from Dino Crisis. Successfully complete the game on the hard difficulty setting with a rank of D to unlock two costumes, C for three, B for four, and A for all five costumes. The three additional costumes are a police miniskirt, disco, and biker outfits.